BDBM50610887 CHEMBL5271224

SMILES COc1cc(\C=c2\c3nc4ccccc4c(=O)n3[nH]c2=O)cc(OC)c1OC

InChI Key InChIKey=SBBHTKBJRAVMMH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50610887   

TargetProstaglandin G/H synthase 2(Human)
Leibniz Institute For Plasma Science and Technology (Inp Greifswald)

Curated by ChEMBL
LigandPNGBDBM50610887(CHEMBL5271224)
Affinity DataIC50: 47nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 30 secs by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Leibniz Institute For Plasma Science and Technology (Inp Greifswald)

Curated by ChEMBL
LigandPNGBDBM50610887(CHEMBL5271224)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human COX-2 using arachidonic acid as substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Leibniz Institute For Plasma Science and Technology (Inp Greifswald)

Curated by ChEMBL
LigandPNGBDBM50610887(CHEMBL5271224)
Affinity DataIC50: 600nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50610887(CHEMBL5271224)
Affinity DataIC50: 668nMAssay Description:Inhibition of recombinant human COX-1 using arachidonic acid as substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Leibniz Institute For Plasma Science and Technology (Inp Greifswald)

Curated by ChEMBL
LigandPNGBDBM50610887(CHEMBL5271224)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed