BDBM50610939 CHEMBL5288200

SMILES Cc1cc(C)cc(Oc2nccc(n2)-c2c(ncn2C2CCN(CCN)CC2)-c2ccc(cc2)C(F)(F)F)c1

InChI Key InChIKey=MBTPASBIFTUPRT-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50610939   

TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50610939(CHEMBL5288200)
Affinity DataIC50: 130nMAssay Description:Inhibition of his 6 tagged BRD4 D1 (unknown origin) expressed in Escherichia coli BL21 (DE3) by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50610939(CHEMBL5288200)
Affinity DataKd:  1.90E+3nMAssay Description:Binding affinity to p38 alpha (unknown origin) assessed as dissociation constant by DiscoverX kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed