BDBM50611295 CHEMBL5289655

SMILES O=c1[nH]n2c(=O)c3ccccc3nc2/c1=C/c1ccc(Br)cc1

InChI Key InChIKey=QXOHUUUSFJPFTN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50611295   

TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611295BDBM50611295(CHEMBL5289655)
Affinity DataIC50: 47nMAssay Description:Inhibition of human COX-2 using acetylcholinesterase as substrate preincubated for 10 mins followed by substrate addition and measured after 30 sec b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611295BDBM50611295(CHEMBL5289655)
Affinity DataIC50: 47nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 30 secs by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Leibniz Institute For Plasma Science and Technology (Inp Greifswald)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611295BDBM50611295(CHEMBL5289655)
Affinity DataIC50: 600nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611295BDBM50611295(CHEMBL5289655)
Affinity DataIC50: 668nMAssay Description:Inhibition of human COX-1 using acetylcholinesterase as substrate preincubated for 10 mins followed by substrate addition and measured after 30 sec b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Leibniz Institute For Plasma Science and Technology (Inp Greifswald)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611295BDBM50611295(CHEMBL5289655)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed