BDBM50611811 CHEMBL3797874

SMILES CN(C)C(=O)Oc1cccc(NC(=O)C2(CN)CCN(CC2)c2ncnc3[nH]c4CCCCc4c23)c1

InChI Key InChIKey=XSRLKVPNDGGLCH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50611811   

TargetLIM domain kinase 2(Human)
Universita Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50611811(CHEMBL3797874)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of LIMK2 (unknown origin) in presence of ATP at 200 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Universita Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50611811(CHEMBL3797874)
Affinity DataIC50: 23nMAssay Description:Inhibition of LIMK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Universita Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50611811(CHEMBL3797874)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant LIMK1 in presence of ATP cofilin as substrate at 25 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universita Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50611811(CHEMBL3797874)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ROCK2 (unknown origin) by Kinase Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed