BDBM50612148 CHEMBL5289136

SMILES [Na+].[O-]S(=O)(=O)Oc1ccc(cc1)-c1nc2ccccc2c(=O)[nH]1

InChI Key InChIKey=SKECNAFRYHASNA-UHFFFAOYSA-M

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50612148   

TargetCoagulation factor XI(Homo sapiens (Human))TBA
LigandPNGBDBM50612148(CHEMBL5289136)
Affinity DataKd:  3.65E+5nMAssay Description:Binding affinity to active site dansylated human DEGR-FXIa assessed as change in fluorescence intensity by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCoagulation factor XI(Homo sapiens (Human))TBA
LigandPNGBDBM50612148(CHEMBL5289136)
Affinity DataIC50:  3.75E+5nMAssay Description:Inhibition of human FXIa using S-2366 as chromogenic substrate preincubated with enzyme for 10 mins followed by substrate addition by spectrophotomet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed