BDBM50612198 CHEMBL5270903

SMILES CN1CC2(CC(C2)n2cc(Nc3nc(OC4(C)CC4)c4nc(c(F)cc4n3)-c3cnc(C)nc3)cn2)C1

InChI Key InChIKey=XGNWCJAZTBIOLY-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50612198   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50612198(CHEMBL5270903)
Affinity DataIC50:  220nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMedPDB3D3D Structure (crystal)

TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50612198(CHEMBL5270903)
Affinity DataIC50:  3nMAssay Description:Inhibition of IRAK4 (unknown origin) in presence of ATP by enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMedPDB3D3D Structure (crystal)