BDBM50612718 CHEMBL5269857

SMILES CCN(CC)c1ccc(\C=C2\N(C)C(=S)N(C3CCCCC3)C2=O)c(O)c1

InChI Key InChIKey=JSMJURUWKJMZCJ-QGOAFFKASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50612718   

TargetCytochrome b-245 heavy chain(Homo sapiens (Human))TBA
LigandPNGBDBM50612718(CHEMBL5269857)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNADPH oxidase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50612718(CHEMBL5269857)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibition of human NOX4 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed