BDBM50612903 CHEMBL5268293

SMILES Cn1c2ccn(-c3c(Cl)cc(cc3Cl)-n3nc(C#N)c(=O)[nH]c3=O)c2ccc1=O

InChI Key InChIKey=FIKDVPCAFAQZPG-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50612903   

TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50612903(CHEMBL5268293)
Affinity DataEC50:  100nMAssay Description:Huh7 cells were cultured in a DMEM medium supplemented with 10% FBS. The cells were inoculated into a 10 cm cell culture dish, proliferated to about ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50612903(CHEMBL5268293)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50612903(CHEMBL5268293)
Affinity DataEC50:  700nMAssay Description:Huh7 cells were cultured in a DMEM medium supplemented with 10% FBS. The cells were inoculated into a 10 cm cell culture dish, proliferated to about ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50612903(CHEMBL5268293)
Affinity DataEC50:  740nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed