BDBM50612908 CHEMBL5281631

SMILES Clc1cc(cc(Cl)c1-n1ccc2n(C3CCC3)c(=O)ccc12)-n1nc(C#N)c(=O)[nH]c1=O

InChI Key InChIKey=WCSJJORVBKHALX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50612908   

TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612908(CHEMBL5281631)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612908(CHEMBL5281631)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed