BDBM50612911 CHEMBL5269031

SMILES CC(C)n1c2ccn(-c3c(Cl)cc(NC(=O)CC(O)=O)cc3Cl)c2ccc1=O

InChI Key InChIKey=CLTUTZGDSOQRBK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50612911   

TargetThyroid hormone receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612911(CHEMBL5269031)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human THRbeta transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612911(CHEMBL5269031)
Affinity DataEC50:  440nMAssay Description:Agonist activity at human THRalpha transfected in Huh7 cells co-transfected with luciferase reporter plasmid assessed as reduction in luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed