BDBM50613166 CHEMBL5290634

SMILES CCc1nc(C)nn1CC(=O)N1CCN(C[C@H]1C)c1sc(nc1-c1cnc(nc1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=AIPQYPCEXRVEFE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50613166   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50613166(CHEMBL5290634)
Affinity DataIC50: 12nMAssay Description:Inhibition of human ERG stably expressed in CHO cells at -80 mV holding voltage by automated QPatch electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50613166(CHEMBL5290634)
Affinity DataIC50: 680nMAssay Description:Antagonist activity at CXCR3 (unknown origin) in human T cells in venous blood assessed as receptor internalization incubated for 30 mins in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed