BDBM50613173 CHEMBL5277205

SMILES C[C@@H]1CN(CCN1C(=O)Cn1cnc(n1)C(C)(C)C)c1sc(nc1-c1cnc(nc1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=GHQQXFVYIYQRDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50613173   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50613173(CHEMBL5277205)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human ERG stably expressed in CHO cells at -80 mV holding voltage by automated QPatch electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50613173(CHEMBL5277205)
Affinity DataIC50: 240nMAssay Description:Antagonist activity at CXCR3 (unknown origin) in human T cells in venous blood assessed as receptor internalization incubated for 30 mins in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed