BDBM50613470 CHEMBL5273860

SMILES Cc1noc2CN=C(c3ccc(Cl)cc3)c3c(ccc(=O)n3C)-c12

InChI Key InChIKey=LBZZXONGPUXRAP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50613470   

TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50613470(CHEMBL5273860)
Affinity DataIC50: 750nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using biotinylated ligand incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50613470(CHEMBL5273860)
Affinity DataEC50:  2.90E+3nMAssay Description:Inhibition of BRD4 BD1 in human MV4-11 cells assessed as reduction of MYC RNA expression after 4 hrs by PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed