BDBM50613519 CHEMBL5281912

SMILES NC(=O)CC[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)c1ccccc1)C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@H]1CSSC[C@H](NC1=O)C(N)=O

InChI Key InChIKey=BBRIVIRAAPNZBF-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50613519   

TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613519(CHEMBL5281912)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613519(CHEMBL5281912)
Affinity DataEC50:  0.360nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells assessed as ERK phosphorylation incubated for 2 hrs by Alphascreen surefire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613519(CHEMBL5281912)
Affinity DataEC50:  0.410nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed