BDBM50613703 CHEMBL5286550

SMILES C[n+]1cn([C@@H]2O[C@H](CNS(=O)(=O)c3ccc(cc3)C(O)=O)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c12

InChI Key InChIKey=AWWBCTMRCFTUFB-XNIJJKJLSA-O

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50613703   

TargetEukaryotic translation initiation factor 4E(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50613703(CHEMBL5286550)
Affinity DataIC50:  1.87E+4nMAssay Description:Inhibition of P32-[alpha-GTP] cap radiolabelled RNA binding to recombinant eIF4E (unknown origin) assessed as decrease in cross linked RNA-eIF4E comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEukaryotic translation initiation factor 4E(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50613703(CHEMBL5286550)
Affinity DataKd:  1.33E+5nMAssay Description:Inhibition of m7GDP fluorescent probe binding to recombinant eIF4E (unknown origin) assessed as dissociation constant by fluorescence polarization as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed