BDBM50613704 CHEMBL5283082

SMILES CC(C)CNC(=S)N(Cc1ccccc1)Cc1cc2cc3OCOc3cc2[nH]c1=O

InChI Key InChIKey=JBPVNZAVPAZFCW-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50613704   

TargetEukaryotic translation initiation factor 4E(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50613704(CHEMBL5283082)
Affinity DataIC50:  3.86E+4nMAssay Description:Inhibition of P32-[alpha-GTP] cap radiolabelled RNA binding to recombinant eIF4E (unknown origin) assessed as decrease in cross linked RNA-eIF4E comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEukaryotic translation initiation factor 4E(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50613704(CHEMBL5283082)
Affinity DataKd:  5.78E+4nMAssay Description:Inhibition of m7GDP fluorescent probe binding to recombinant eIF4E (unknown origin) assessed as dissociation constant by fluorescence polarization as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed