BDBM50613948 CHEMBL5270456

SMILES Cc1noc(C)c1-c1ccc2[nH]c(=O)cc(NCc3ccccc3)c2c1

InChI Key InChIKey=ZZEQMSXTKAJTLH-UHFFFAOYSA-N

Data  6 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50613948   

TargetBromodomain-containing protein 4(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50613948(CHEMBL5270456)
Affinity DataKd:  44nMAssay Description:Inhibition of BRD4 bromodomain 1/2 (unknown origin) assessed as dissociation constant by DiscoveRx BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50613948(CHEMBL5270456)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of BRD4 bromodomain 1/2 (unknown origin) by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50613948(CHEMBL5270456)
Affinity DataIC50: 6.77E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2C19(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50613948(CHEMBL5270456)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50613948(CHEMBL5270456)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50613948(CHEMBL5270456)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50613948(CHEMBL5270456)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed