BDBM50614116 CHEMBL5285143

SMILES CC(C)COC(=O)Nc1cc2c(cn1)N(C(C)=O)C(C)(C)C21CCCCC1

InChI Key InChIKey=UPYHHVKVCIAXTB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50614116   

TargetThyrotropin receptor(Rattus norvegicus)TBA
LigandPNGBDBM50614116(CHEMBL5285143)
Affinity DataIC50:  39nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50614116(CHEMBL5285143)
Affinity DataIC50:  1.00E+4nMAssay Description:Antagonist activity at human FSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetThyrotropin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50614116(CHEMBL5285143)
Affinity DataIC50:  82nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed