BDBM50614130 CHEMBL5283557

SMILES O=C1CC2CCc3ccsc3C2=NN1Cc1ccc(CN2CCN(Cc3ccccc3)CC2)cc1

InChI Key InChIKey=FMHFUABJEGMXDA-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50614130   

Target5-hydroxytryptamine receptor 1A(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50614130(CHEMBL5283557)
Affinity DataKi:  786nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK cell membrane incubated for 120 mins by microplate beta scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50614130(CHEMBL5283557)
Affinity DataKi:  1.26E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK cell membrane incubated for 60 mins by microplate beta scintillation counting ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50614130(CHEMBL5283557)
Affinity DataKi:  2.11E+3nMAssay Description:Displacement of [3H]SB269970 from human 5-HT7 receptor expressed in HEK cell membrane incubated for 60 mins by microplate beta scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50614130(CHEMBL5283557)
Affinity DataIC50: 3.65E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCholinesterase(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50614130(CHEMBL5283557)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed