BDBM50614186 CHEMBL5284165

SMILES COc1cc(OC)cc(c1)-c1nn([C@H]2CCN(C2)C(=O)C=C)c2ncnc(N)c12

InChI Key InChIKey=UIIMEJDKBXGCCI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50614186   

TargetFibroblast growth factor receptor 2(Human)
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50614186(CHEMBL5284165)
Affinity DataIC50: 207nMAssay Description:Inhibition of human recombinant cytoplasmic domain FGFR2 (8 to 134 residues) incubated for 120 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50614186(CHEMBL5284165)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human EGFR del19/T790M using biotinEEPLYWSFPAKKK-NH2 as substrate incubated for 120 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed