BDBM50614187 CHEMBL5273555

SMILES COc1cc(CCc2nn([C@H]3CCN(C3)C(=O)C=C)c3ncnc(N)c23)cc(OC)c1

InChI Key InChIKey=IKDKTOHLOYUENF-HNNXBMFYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50614187   

TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50614187(CHEMBL5273555)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human EGFR del19/T790M using biotinEEPLYWSFPAKKK-NH2 as substrate incubated for 120 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50614187(CHEMBL5273555)
Affinity DataIC50:  239nMAssay Description:Inhibition of human recombinant cytoplasmic domain FGFR2 (8 to 134 residues) incubated for 120 mins by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed