BDBM50614304 CHEMBL5285335

SMILES [H][C@]12CN(C[C@@]1([H])NCCC2)c1cc(Nc2ccc(Oc3ccc4[nH]ncc4c3)c(F)c2)nc(N)n1

InChI Key InChIKey=XRNUYXYXODWZHA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50614304   

TargetRho-associated protein kinase 1(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50614304(CHEMBL5285335)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant ROCK1 using S6-peptide as substrate as substrate preincubated for 10 mins followed by 33P-labeled ATP addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed