BDBM50614608 CHEMBL2430327

SMILES O=C1C(=Cc2ccc(-c3ccccc3[N+](=O)[O-])o2)C(=O)N(c2ccccc2)C(=S)N1c1ccccc1

InChI Key InChIKey=JAQHSNBIJVAUAN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50614608   

TargetSerine protease HTRA2, mitochondrial(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614608BDBM50614608(CHEMBL2430327)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant human HTRA2 using H2-OPT as substrate assessed as increase in fluorescence and measured for 2 hrs by fluorescent plate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSerine protease HTRA1(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614608BDBM50614608(CHEMBL2430327)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human HTRA1 using H2-OPT as substrate assessed as increase in fluorescence and measured for 2 hrs by fluorescent plate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed