BDBM50614609 CHEMBL5271361

SMILES CC1OC(=O)Cc2c(Cl)c(O)cc(O)c2C(=O)\C(C)=C\CCC1(C)C

InChI Key InChIKey=SJMLJWOLGMOTLG-UXBLZVDNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50614609   

TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614609(CHEMBL5271361)
Affinity DataIC50:  30nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed

TargetSignal transducer and activator of transcription 6(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614609(CHEMBL5271361)
Affinity DataIC50:  79nMAssay Description:Inhibition of IL-4 induced STAT6 signaling in human HepG2 cells harboring pRL-EF1alpha, pGL3-TK-7xN4 and TOPO-Stat6 plasmid assessed as luciferase ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed