BDBM50614988 CHEMBL5269824

SMILES Cc1csc([C@@]2(CN)[C@@H]3CCN(c4nc5nc(Sc6cccnc6C(F)(F)F)cnc5[nH]4)C[C@@H]32)n1

InChI Key InChIKey=HFQCDZLKGZKHKU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50614988   

LigandChemical structure of BindingDB Monomer ID 50614988BDBM50614988(CHEMBL5269824)
Affinity DataIC50: 9nMAssay Description:Allosteric inhibition of recombinant human SHP2 using IRS1 peptide and DiFMUP as substrate incubated for 30 mins followed by DiFMUP addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed