BDBM50614994 CHEMBL5275479

SMILES NC[C@]1(c2ccsc2)[C@@H]2CCN(c3cnc4c(-c5cccc(Cl)c5Cl)n[nH]c4n3)C[C@@H]21

InChI Key InChIKey=NNHSFUJHEDZYGF-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50614994   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
IRBM

Curated by ChEMBL

LigandBDBM50614994(CHEMBL5275479)Copy SMILESCopy InChI

Affinity DataIC50: 8nMAssay Description:Allosteric inhibition of recombinant human SHP2 using IRS1 peptide and DiFMUP as substrate incubated for 30 mins followed by DiFMUP addition and meas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/22/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
IRBM

Curated by ChEMBL

LigandBDBM50614994(CHEMBL5275479)Copy SMILESCopy InChI

Affinity DataIC50: 109nMAssay Description:Inhibition of human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/22/2024
Entry Details
Copy BDB DOIPubMed
Copy reaction URL