BDBM50615008 CHEMBL5273026

SMILES Cn1cc2c(Cl)c(-c3n[nH]c4nc(N5C[C@@H]6[C@H](C5)[C@@]6(CN)c5ccccn5)cnc34)ccc2n1

InChI Key InChIKey=UNUGORATTYWTNE-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50615008   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
IRBM

Curated by ChEMBL

LigandBDBM50615008(CHEMBL5273026)Copy SMILESCopy InChI

Affinity DataIC50: 5nMAssay Description:Allosteric inhibition of recombinant human SHP2 using IRS1 peptide and DiFMUP as substrate incubated for 30 mins followed by DiFMUP addition and meas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/22/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
IRBM

Curated by ChEMBL

LigandBDBM50615008(CHEMBL5273026)Copy SMILESCopy InChI

Affinity DataIC50: 8.96E+3nMAssay Description:Inhibition of human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/22/2024
Entry Details
Copy BDB DOIPubMed
Copy reaction URL