BDBM50615066 CHEMBL5266595

SMILES CCn1c(=O)c(-c2c(Cl)cccc2Cl)cc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21

InChI Key InChIKey=CVBFLZPOJZBXKW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50615066   

TargetWee1-like protein kinase(Human)
Emd Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615066BDBM50615066(CHEMBL5266595)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human full length GST-tagged WEE1 expressed in insect cells incubated for 15 mins followed by ATP addition by ADP Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Emd Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615066BDBM50615066(CHEMBL5266595)
Affinity DataIC50: 148nMAssay Description:Inhibition of WEE1 in human U2OS cells incubated for 1 hr by mesoscale discovery assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Emd Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615066BDBM50615066(CHEMBL5266595)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human N-terminal His6-tagged recombinant full-length PLK1 expressed in baculovirus infected Sf9 cells incubated for 15 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed