BDBM50615096 CHEMBL5287229
SMILES COc1cc(ccc1Nc1ncc(C(=O)OC(C)C)c(n1)-c1cn(C)c2ccccc12)N1CCC(N)CC1
InChI Key InChIKey=BUTQOIKDMKIAMT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50615096
Affinity DataIC50: 0.350nMAssay Description:Inhibition of wild type EGFR (unknown origin) using TK-substrate preincubated with enzyme for 30 mins followed by substrate and ATP addition for 25 m...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin) using TK-substrate preincubated with enzyme for 30 mins followed by substrate and ATP ad...More data for this Ligand-Target Pair
Affinity DataIC50: 0.560nMAssay Description:Inhibition of EGFR L858R/C797S mutant (unknown origin) using TK-substrate preincubated with enzyme for 30 mins followed by substrate and ATP addition...More data for this Ligand-Target Pair