BDBM50615433 CHEMBL5270506

SMILES COc1cnc(Nc2ccc(cc2)N2CCN(C)CC2)nc1Nc1ccc2[nH]ccc2c1

InChI Key InChIKey=AZFJKCKOFYZDEI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50615433   

TargetEpidermal growth factor receptor(Human)
Nanjing University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50615433(CHEMBL5270506)
Affinity DataIC50: 155nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Nanjing University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50615433(CHEMBL5270506)
Affinity DataIC50: 224nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Nanjing University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50615433(CHEMBL5270506)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed