BDBM50615435 CHEMBL5271043

SMILES CN1CCN(CC1)c1ccc(Nc2ncc(F)c(Nc3ccc4[nH]ccc4c3)n2)cc1

InChI Key InChIKey=GULVHNBTUFJZLT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50615435   

TargetEpidermal growth factor receptor(Human)
Nanjing University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50615435(CHEMBL5271043)
Affinity DataIC50: 181nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Nanjing University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50615435(CHEMBL5271043)
Affinity DataIC50: 232nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Nanjing University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50615435(CHEMBL5271043)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed