BDBM50615436 CHEMBL5287550

SMILES CN1CCN(CC1)c1ccc(Nc2ncc(Br)c(Nc3ccc4[nH]ccc4c3)n2)cc1

InChI Key InChIKey=SSWRZDDBJSGSPL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50615436   

TargetEpidermal growth factor receptor(Human)
Nanjing University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50615436(CHEMBL5287550)
Affinity DataIC50: 35nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Nanjing University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50615436(CHEMBL5287550)
Affinity DataIC50: 53nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Nanjing University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50615436(CHEMBL5287550)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed