BDBM50615440 CHEMBL5288264

SMILES CN1CCN(CC1)c1ccc(Nc2ncc(Br)c(Nc3ccc4[nH]c(Cc5cccc(F)c5)cc4c3)n2)cc1

InChI Key InChIKey=WGYUCQBGAJNBHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50615440   

TargetEpidermal growth factor receptor(Human)
Nanjing University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50615440(CHEMBL5288264)
Affinity DataIC50: 49nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Nanjing University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50615440(CHEMBL5288264)
Affinity DataIC50: 325nMAssay Description:Inhibition of wild type EGFR (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed