BDBM50615454 CHEMBL5269747

SMILES COc1cc(N2CCN(C)CC2)c(NC(=O)C=C)cc1Nc1ncc(Br)c(Nc2ccc3CCCc3c2)n1

InChI Key InChIKey=RHAOZWQPTQQXGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50615454   

TargetEpidermal growth factor receptor(Human)
Nanjing University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50615454(CHEMBL5269747)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Nanjing University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50615454(CHEMBL5269747)
Affinity DataIC50: 203nMAssay Description:Inhibition of wild type EGFR (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed