BDBM50615472 CHEMBL5275223

SMILES N#Cc1cn(-c2ccccc2)c2c(ncnc12)N1CCN(CCc2c[nH]c3ccccc23)CC1

InChI Key InChIKey=AUYSDBKLMPCVQL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50615472   

TargetMultidrug resistance-associated protein 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50615472(CHEMBL5275223)
Affinity DataIC50: 328nMAssay Description:Inhibition of MRP1 in human NCI-H69AR cells incubated for 180 mins in presence of daunorubicin by flow cytometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50615472(CHEMBL5275223)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of P-gp (unknown origin) incubated for 30 mins by calcein AM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed