BDBM50615657 CHEMBL4099342

SMILES COc1ccc2[C@@H](N(CCc2n1)C(=O)[C@@H]1C[C@H](CC(O)=O)C1)C(=O)Nc1cc2CCC(C)(C)c2c(F)c1

InChI Key InChIKey=ICMFYVOUDGRBLG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50615657   

TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50615657(CHEMBL4099342)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of RORgammat (unknown origin) by binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50615657(CHEMBL4099342)
Affinity DataIC50: 1.90nMAssay Description:Inverse agonist activity at RORgammat (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 1 hr by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50615657(CHEMBL4099342)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of RORgammat (unknown origin) by cell based reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed