BDBM50615676 CHEMBL5274502

SMILES COc1cc(cc(OC)c1CN1CCN(CCOCCOCCOc2cc(ccc2CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(F)CC2)C(C)(C)C)-c2scnc2C)CC1)-c1cn(C)c(=O)c2cnccc12

InChI Key InChIKey=MXAKQOVZPDLCDK-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50615676   

TargetElongin-C(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50615676(CHEMBL5274502)
Affinity DataKd:  60nMAssay Description:Co-operative binding affinity to 6His-tagged human VHL/ElonginC/ElonginB expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetElongin-C(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50615676(CHEMBL5274502)
Affinity DataKd:  70nMAssay Description:Binding affinity to 6His-tagged human VHL/ElonginC/ElonginB expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant using FA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetElongin-C(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50615676(CHEMBL5274502)
Affinity DataKd:  83nMAssay Description:Co-operative binding affinity to 6His-tagged human VHL/ElonginC/ElonginB expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetElongin-C(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50615676(CHEMBL5274502)
Affinity DataKd:  87nMAssay Description:Binding affinity to 6His-tagged human VHL/ElonginC/ElonginB expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by ITC a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed