BDBM50615775 CHEMBL5279860

SMILES CC(C)(O)[C@H]1CC[C@@H](CC1)NC(=O)c1cnc2cc(ncc2c1)N1CCC1

InChI Key InChIKey=YBOJDFGHCNHNOW-QAQDUYKDSA-N

Data  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50615775   

TargetHematopoietic prostaglandin D synthase(Rattus norvegicus)TBA
LigandPNGBDBM50615775(CHEMBL5279860)
Affinity DataEC50:  24nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615775(CHEMBL5279860)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB