BDBM50616102 CHEMBL5405012

SMILES CC(C)[C@H](NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](C)C(=O)C(=O)NCCCCc1ccccc1

InChI Key InChIKey=YFGBSZIJBXPJHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50616102   

TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616102BDBM50616102(CHEMBL5405012)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human PARL using KSp106 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616102BDBM50616102(CHEMBL5405012)
Affinity DataIC50: 44nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616102BDBM50616102(CHEMBL5405012)
Affinity DataIC50: 132nMAssay Description:Inhibition of C-terminal His-tagged full length Escherichia coli GIpG expressed in Escherichia coli C43 (DE3) using Ac-RVRHA-4mc as substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616102BDBM50616102(CHEMBL5405012)
Affinity DataEC50:  1.47E+3nMAssay Description:Inhibition of GlpG in wild-type Escherichia coli MC4100 using MBP-Flag-LacYTMD2-Trx as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed