BDBM50616448 CHEMBL5441116

SMILES CC(C)(C)NC(=O)CC[C@H](NC(=O)C(=O)c1c[nH]c2ccccc12)C(=O)NCc1cccc(c1)B(O)O

InChI Key InChIKey=HAUWDWPKCJZHJU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50616448   

TargetProteasome subunit beta type-5(Human)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50616448(CHEMBL5441116)
Affinity DataIC50: 85nMAssay Description:Inhibition of human 20s constitutive proteasome beta-5cMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetProteasome subunit beta type-8(Human)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50616448(CHEMBL5441116)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of human 20s immunoproteasome beta-5i subunitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetProteasome subunit beta type-9(Human)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50616448(CHEMBL5441116)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of human 20s immunoproteasome beta-1i subunitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetProteasome subunit beta type-2(Human)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50616448(CHEMBL5441116)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of human 20s constitutive proteasome beta-2c subunitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetProteasome subunit beta type-1(Human)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50616448(CHEMBL5441116)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of human 20s constitutive proteasome beta-1cMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetProteasome subunit beta type-10(Human)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50616448(CHEMBL5441116)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of human 20s immunoproteasome beta-2i subunitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed