BDBM50616629 CHEMBL5413417

SMILES CC(C)c1ccc(cc1)-c1cccc(c1)S(=O)(=O)N1CCCC(C1)c1cccc(OC(C)(C)C(=O)NS(=O)(=O)c2cccs2)c1

InChI Key InChIKey=XELHDTJJEQFRGH-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50616629   

TargetCatenin beta-1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50616629(CHEMBL5413417)
Affinity DataKd:  320nMAssay Description:Binding affinity to full-length beta-catenin (1 to 781 residues) (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetB-cell CLL/lymphoma 9 protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50616629(CHEMBL5413417)
Affinity DataIC50: 910nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetB-cell CLL/lymphoma 9 protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50616629(CHEMBL5413417)
Affinity DataIC50: 940nMAssay Description:Inhibition of beta-catenin/BCL9 protein-protein interaction in Wnt-dependent human HCT-116 cells assessed as reduction in Axin2 expression level by q...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed