BDBM50617703 CHEMBL5413223

SMILES CN(Cc1ccccc1)c1ncnc2[nH]c(nc12)-c1ccc(CO)cc1

InChI Key InChIKey=NNMVDGFJIPMXNA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50617703   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50617703(CHEMBL5413223)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of CSF1R (unknown origin) using FRET-peptide as substrate incubated in presence of ATP by FRET based Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50617703(CHEMBL5413223)
Affinity DataIC50: 109nMAssay Description:Inhibition of EGFR (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50617703(CHEMBL5413223)
Affinity DataIC50: 330nMAssay Description:Inhibition of CSF1-induced CSF1R signalling in mouse BMDM cells assessed as reduction in ERK1/2 phosphorylation preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed