BDBM50617762 CHEMBL5433135

SMILES COc1cc(COc2ccc(-c3noc(-c4ccc5[nH]ncc5c4)n3)cc2)cc(OC)c1OC

InChI Key InChIKey=MMVVUYZEFSZMKK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617762   

TargetAmine oxidase [flavin-containing] B(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617762BDBM50617762(CHEMBL5433135)
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant MAO-B assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate incubated for 50 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617762BDBM50617762(CHEMBL5433135)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in Pichia pastoris assessed as inhibition constant using MMTP as substrate by Morrison equation based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed