BDBM50617901 CHEMBL5418520

SMILES CC(Nc1ccc2c(-c3ccc(C)cc3)c(C#N)c(=O)n(Cc3ccccc3)c2c1)c1ccccn1

InChI Key InChIKey=GUNYGQDXNYUUNH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617901   

LigandChemical structure of BindingDB Monomer ID 50617901BDBM50617901(CHEMBL5418520)
Affinity DataIC50: 15nMAssay Description:Inhibition of PDE1C (147 to 531 residues) (unknown origin) using 3H-cGMP as substrate incubated for 15 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617901BDBM50617901(CHEMBL5418520)
Affinity DataIC50: 578nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed