BDBM50617969 CHEMBL5406611

SMILES Cc1c(ccc2nc([nH]c12)-c1cccc(CNCCO)c1)-c1ccccc1

InChI Key InChIKey=NYQPBXJWCKKTJV-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50617969   

TargetV-type immunoglobulin domain-containing suppressor of T-cell activation(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617969(CHEMBL5406611)
Affinity DataKd:  256nMAssay Description:Binding affinity to human VISTA assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetV-type immunoglobulin domain-containing suppressor of T-cell activation(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617969(CHEMBL5406611)
Affinity DataKd:  470nMAssay Description:Binding affinity to human VISTA assessed as dissociation constant by SPR binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617969(CHEMBL5406611)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Eu-tagged PD-1 (unknown origin)/C-terminal Fc fusion (human IgG1)/Avi-tagged biotinylated human PDL1 (19 to 239 residues) extracted fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetV-type immunoglobulin domain-containing suppressor of T-cell activation(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617969(CHEMBL5406611)
Affinity DataKd:  2.70E+3nMAssay Description:Binding affinity to human VISTA assessed as dissociation constant incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetV-type immunoglobulin domain-containing suppressor of T-cell activation(Mus musculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50617969(CHEMBL5406611)
Affinity DataKd:  6.80E+3nMAssay Description:Binding affinity to mouse VISTA assessed as dissociation constant incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed