BDBM50617970 CHEMBL5422970

SMILES Cc1c(ccc2nc([nH]c12)-c1ccc(CNCCO)cc1)-c1ccccc1

InChI Key InChIKey=MDCDXCBDSVEJAA-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617970   

TargetV-type immunoglobulin domain-containing suppressor of T-cell activation(Human)
Wenzhou Medical University Lishui Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617970BDBM50617970(CHEMBL5422970)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of N-terminal His-tagged human recombinant VISTA (1 to 161 residues) transfected in human Expi293 cells incubated for 60 mins by ELISA ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetV-type immunoglobulin domain-containing suppressor of T-cell activation(Human)
Wenzhou Medical University Lishui Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617970BDBM50617970(CHEMBL5422970)
Affinity DataKd:  1.13E+3nMAssay Description:Binding affinity to human VISTA assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed