BDBM50618161 CHEMBL5429160

SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)[C@H](CC)[C@]4([H])C[C@@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)O[C@]1([H])O[C@H](CC([O-])=O)[C@@H](O)[C@H](O)[C@H]1O)[C@H](C)CCOS([O-])(=O)=O

InChI Key InChIKey=YKWYXWYRDFKIAP-UHFFFAOYSA-L

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50618161   

TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50618161(CHEMBL5429160)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at glutathione transferase-tagged human FXR ligand binding domain assessed as biotinylated Src1 peptide recruitment incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50618161(CHEMBL5429160)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TGR5 receptor in human NCI-H716 cells assessed as activation of intracellular cAMP production incubated for 1 hr by HTR-FRET assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed