BDBM50618570 CHEMBL5412547

SMILES ONC(=O)c1ccc(CNC(=O)c2ccnc(c2)-c2ccc(OCc3ccccc3)cc2)cc1

InChI Key InChIKey=BIFRNKHUZHRQGI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50618570   

TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50618570(CHEMBL5412547)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of C-terminal FLAG tagged recombinant human HDAC1 expressed in Sf9 cells using Ac-peptide as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50618570(CHEMBL5412547)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as a substrate by amplex red/HRP based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed