BDBM50618754 CHEMBL5420728

SMILES CS(=O)(=O)c1sc(c2CC(F)(F)[C@@H](O)c12)-c1ccc(F)cc1

InChI Key InChIKey=DDQZGFIXHMUCKK-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50618754   

TargetEndothelial PAS domain-containing protein 1(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50618754(CHEMBL5420728)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of HIF-2alpha transcriptional activity in human 786-0 cells transfected with HRE-luc2P assessed as decrease in luminescence incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEndothelial PAS domain-containing protein 1(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50618754(CHEMBL5420728)
Affinity DataKd:  830nMAssay Description:Binding affinity to human recombinant HIF-2alpha (240 to 350 residues) assessed as as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed