BDBM50618896 CHEMBL5421558

SMILES COc1cc(cc2CCN(CC(F)(F)F)C(=O)c12)-c1cnc(Nc2cc(nc(C)n2)N2CCOCC2)s1

InChI Key InChIKey=XOZORSAAPNHXFP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50618896   

TargetSerine/threonine-protein kinase SIK2(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50618896(CHEMBL5421558)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of SIK2 (unknown origin) using AMARA as substrate buffer incubated for 60 mins followed by addition of ADP-Glo reagent further incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK3(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50618896(CHEMBL5421558)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of SIK3 (unknown origin) using AMARA as substrate buffer incubated for 60 mins followed by addition of ADP-Glo reagent further incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK1(Human)
Insilico Medicine Shanghai

Curated by ChEMBL
LigandPNGBDBM50618896(CHEMBL5421558)
Affinity DataIC50: 88nMAssay Description:Inhibition of SIK1 (unknown origin) using AMARA as substrate buffer incubated for 60 mins followed by addition of ADP-Glo reagent further incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed